What are the post-transplant complications for allogeneic patients?
- At risk for infections for a longer period of time than patients undergoing autologous transplantation
- More susceptible to immune complications such as graft versus-host disease (GVHD) and rejection of the graft.
- Requires combination medications to prevent infection and GVHD.
Once the preparative regimen is completed, blood/marrow stem cells are infused via your central venous catheter. This process is similar to receiving a blood transfusion.
- Stem cells then find their own way to the bone marrow.
- Recovery of the white blood cell count takes about 15-30 days after the stem cell infusion.
- Blood and platelet transfusions will occur
- Antibiotics will be given to prevent infection
Definition and types of transplants
The next decision to be made is what type of stem cell source will be used. This decision is based on numerous considerations, including the state of your health and the specific disease you have.